经鼻内镜视神经减压治疗外伤性视神经病变的研究进展

Research advances in endoscopic transnasal optic nerve decompression for traumatic optic neuropathy

  • 摘要: 外伤性视神经病变(traumatic optic neuropathy,TON)是由于颅面部外伤引起的视神经损伤,表现为视力急剧下降 或完全失明。TON的临床干预措施包括单纯观察、糖皮质激素治疗和视神经减压,但其最佳治疗方法存在争议。随着内镜 技术的发展,经鼻内镜视神经减压术逐渐成为治疗TON的主流方法。尽管如此,目前缺乏高质量的随机对照试验评估其疗 效,且治疗效果受多种因素影响,包括手术时机、视力丧失严重程度、视神经管骨折、视神经鞘切开及筛窦和/或蝶窦内出 血等。本文就近年来经鼻内镜视神经减压治疗TON的临床疗效、预后因素及技术创新等进行综述。

     

    Abstract: Traumatic optic neuropathy (TON) is caused by craniofacial trauma leading to optic nerve damage, characterized by a sudden and significant decrease in vision or complete blindness. Clinical interventions for TON include simple observation, corticosteroid therapy, and optic nerve decompression. However, there is controversy over which treatment method is optimal. With advancements in endoscopic techniques, endoscopic transnasal optic nerve decompression (ETOND) has increasingly become a mainstream method for treating TON. Despite this, there is a lack of high-quality randomized controlled trials to evaluate its efficacy. Furthermore, treatment outcomes are influenced by several factors, including the timing of surgery, the severity of vision loss, optic canal fractures, optic nerve sheath incision, and hemorrhage within the ethmoid and/or sphenoid sinuses. This review provides an overview of the recent clinical efficacy, prognostic factors, and technological innovations in ETOND for the treatment of TON.

     

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