基础代谢率与心血管代谢疾病的相关性研究现状

The current status of the research on the correlation between basal metabolic rate and cardiovascular metabolic diseases

  • 摘要:
    心血管代谢疾病(cardiovascular metabolic disease,CMD)是全球公共卫生问题,严重威胁人类健康。基础代谢率(basal metabolic rate,BMR)作为反映机体代谢状态的关键指标,与心血管代谢疾病的相关性备受关注。相关研究揭示基础代谢率在冠心病、高血压、糖尿病等心血管代谢疾病进程中的潜在作用。然而,当前研究在多方面仍存在局限及面临诸多挑战,基础代谢率的精准测量受多种因素干扰;两者相关性的深层机制尚未完全清楚,涉及神经内分泌、细胞代谢、炎症通路等多个复杂因子的交互作用有待进一步研究。本文通过系统总结和分析基础代谢率与冠心病、高血压、糖尿病、肥胖等心血管代谢疾病的相关性,深入分析当前研究的进展,以期为进一步研究两者在诊断和治疗方面的转化应用提供参考依据,为疾病的早期防治和管理提供帮助。

     

    Abstract:
    Cardiovascular metabolic disease (CMD) is a global public health issue that seriously threatens human health. Basal metabolic rate(BMR), a key indicator reflecting the body's metabolic state, has drawn significant attention regarding its correlation with cardiovascular metabolic diseases. Relevant studies have revealed the potential role of the basal metabolic rate in the progression of cardiovascular metabolic diseases such as coronary heart disease, hypertension, and diabetes. However, current research still has limitations in many aspects and faces numerous challenges. The accurate measurement of the basal metabolic rate is interfered by multiple factors. The underlying mechanisms of the correlation between them remain incompletely understood, and the interactions of multiple complex factors involving neuroendocrine, cellular metabolism, inflammatory pathways, etc., await further investigation. This article systematically summarizes and analyzes the correlation between the basal metabolic rate and cardiovascular metabolic diseases such as coronary heart disease, hypertension, diabetes, and obesity, and deeply analyzes the current research progress, aiming to provide a reference for further research on the translational applications of the two in diagnosis and treatment, and to contribute to the early prevention, treatment, and management of diseases.

     

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