基于 CTA 影像学的 Stanford B 型主动脉夹层破口最大直径精准测量研究

Precise measurement of the maximum diameter of type B aortic dissection tears based on CTA imaging

  • 摘要:
    背景 破口尺寸对于主动脉夹层的发生、进展及预后具有重要的影响。随着腔内治疗技术的发展,国内外均报道了利用封堵器封堵破口的案例,该技术成功的关键在于精准测量破口的大小,然而目前并无标准的破口尺寸测量方法。目的 利用CTA影像精准测量主动脉夹层破口的最大直径,为破口封堵器的选择提供依据。方法 选取2022年1月 — 2024年1月中国Stanford B型主动脉夹层多中心临床注册研究(ROBUST)纳入的主动脉夹层患者,基于其CTA影像数据,借助Mimics软件的动态区域增长及布尔运算功能三维重建破口并在二维平面测量其最大直径,应用 3-Matic软件测量三维重建破口最大直径,对比分析三维重建测量法和二维平面测量法的结果。结果 共纳入Stanford B型主动脉夹层患者102例,其中男性91例,女性11例,平均年龄(51.47±12.36)岁,共观测破口146个。三维重建测得破口最大直径显著大于二维平面测量结果M(IQR):14.02(6.99 ~ 22.07) mm vs 10.28(4.86 ~ 15.92) mm,P<0.001。按主动脉Ishimaru分区对比显示:Z3-Z9各个区域破口最大直径的三维重建测量结果均大于二维平面测量结果(P<0.05)。结论 基于CTA影像三维重建破口为主动脉夹层破口最大直径的测量提供了新的方法选择,对于封堵器型号选择具有重要的指导意义。

     

    Abstract:
    Background The size of the intimal tear significantly influences the occurrence, progression, and prognosis of aortic dissection. With the development of endovascular treatment techniques, both domestic and international studies have documented successful clinical cases of aortic tear occlusion using endograft devices. The success of this technique relies heavily on the accurate measurement of the tear size. However, there is currently no standardized method for measuring the tear size. Objective To accurately measure the maximal diameter of the aortic dissection tear by utilizing CTA imaging, so as to provide guidance for the selection of tear occluders.Methods Patients with Stanford type B aortic dissection enrolled in the ROBUST multicenter registry in China from January 2022 to January 2024 were selected. Based on their computed tomography angiography (CTA) imaging data, the tears were three-dimensionally reconstructed using Mimics software with dynamic region growing and Boolean operations. The maximum diameter of the entry tear was measured both on two-dimensional CTA images using Mimics software and the three-dimensional reconstruction using 3-Matic software. The measurements from these two methods were then compared and analyzed.Results A total of 102 patients with Stanford type B aortic dissection were enrolled, comprising 91 males and 11 females, with a mean age of (51.47 ± 12.36) years. Totally 146 entry tears were identified and analyzed. The maximum diameter of the tears measured by three-dimensional reconstruction was significantly larger than that measured in the twodimensional plane (MIQR: 14.02(6.99 - 22.07) mm vs 10.28(4.86 - 15.92) mm, P<0.001. Stratified analysis based on the Ishimaru aortic zoning system demonstrated that three-dimensional reconstruction measurements consistently yielded larger maximum tear diameters compared to two-dimensional planar quantification across all Zone3-Zone9 anatomical segments (P<0.05). Conclusion 3D reconstruction of tears based on CTA images offers a novel methodological option for measuring the maximum diameter of aortic dissection entry sites, providing critical guidance for endovascular occluder device sizing.

     

/

返回文章
返回