Abstract: Ojbective: To investigate the etiological characteristics of deep infection caused by candida.Methods: The routine methods use for identifying Candida included: inoculate on CHROMagar and Corn-Tween 80 agar、 gemma-form test、 commercial kit included API 20C AUX and VITEK YBC card、 blood culture using VITAL.Results: From May 2004 to August 2007,we separated 749 strains of Candida from deep infected specimens.The ratio of different Candida were: Candida albicans 41.79%、 Candida tropicalis 24.17%、 Candida glabrata 12.02%、 Candida parapsilosis 12.95%、 Candida krusei 2%、 other Candida 7.07%.Conclusion: Candida albicans is the most common type,but its ratio is decreasing compared with the past.The ratios of Candida glabrata and Candida parapsilosis are increasing significantly.