Abstract: Ojbective: To investigate the result of healing solitary bone cysts by steroid or autologous bone marrow injection.Methods: There were 64 definited solitary bone cysts after union of pathologic fracture injected with steroid or autologous bone marrow after percutaneous aspiration.The result of radiographic inspection after injection and the follow up had been retrospective analyzed.Results: The results of autologous bone marrow（77.8%） was better than the steroid（43.2%）.In the group of patients who were less 10 years of age with cysts,the cure rate of autologous bone marrow（75.0%） was higher than the steroid（25.0%）.There was no difference in the group of who were over 10 years of age with cysts（57.1% with 80.0%）.Conclusion: The results of autologous bone marrow injected for solitary bone cysts is better than the steroid,and it is a safe、 highly effective and minimally invasive way to cure simple bone cyst.