糖化血红蛋白水平与老年急性冠脉综合征患者住院期间心血管事件的临床分析

Correlation between HbA1c and cardiovascular events in hospitalized elderly patients with acute coronary syndrome

  • 摘要: 目的 本研究针对老年患者住院期间心血管事件的临床分析,探讨糖化血红蛋白(hemoglobin Alc,HbA1c)水平与心血管事件发生率的相关性。 方法 选择2009年6月-2011年6月在本院老年高干病房住院的老年急性冠脉综合征(acutecornary syndrome,ACS)患者203例,根据HbA1c水平分为Ⅰ组(HbA1c<7.0%)和Ⅱ组(HbA1c≥7.0%)。记录一般临床资料、测定空腹血糖及HbA1c水平,并观察住院期间恶性心血管事件。 结果 Ⅱ组空腹血糖(58.65% vs 56.38%)及HbA1c水平(7.83%±1.58% vs 6.17%±1.89%)均显著高于Ⅰ组(P<0.01)。在住院期间,Ⅱ组恶性心律失常(23.85% vs 11.70%)、心力衰竭(32.11% vs 17.02%)、再发心绞痛(26.61% vs 13.83%)等的发生率均显著高于Ⅰ组(P<0.05)。 结论 高HbA1c水平的老年ACS患者住院期间恶性心血管事件发生率较高。

     

    Abstract: Objective To study the correlation between HbA1c and cardiovascular events in hospitalized elderly patients with acute coronary syndrome(ACS). Methods Two hundred and three elderly ACS patients admitted to our department from June 2009 to June 2011 were divided into group A and group B according to their HbA1c.Their general clinical data were recorded,their fasting blood glucose level and HbA1c were measured,and their malignant cardiovascular events were observed. Results The fasting blood glucose(58.65% vs 56.38%) and HbA1c levels(7.83%±1.58% vs 6.17%±1.89%) were significantly higher in group B than in group A(P<0.01).The incidence of arrhythmia(23.85% vs 11.70%),heart failure(32.11% vs 17.02%) and recurrence of angina pectoris(26.61% vs 13.83%) was significantly higher in group B than in group A(P<0.05). Conclusion The incidence of malignant cardiovascular events is relatively high in hospitalized ACS patients with a high HbA1c level.

     

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