多发性大动脉炎支架内再狭窄影响因素分析

Influencing factors for restenosis in patients with Takayasu’s arteritis

  • 摘要: 目的 探讨多发性大动脉炎(takayasu's arteritis,TA)血管内支架置入术后再狭窄的预测因素及原因,为临床干预提供依据。 方法 将2000年1月-2011年8月在本院心内科行血管内支架置入术的50例TA患者纳入研究。分为血管内支架置入无狭窄组和再狭窄组,分别比较两组临床基本资料、血管造影影像特征。采用Logistic回归模型分析多发性大动脉炎支架内狭窄的独立危险因素。 结果 与无狭窄组比较,再狭窄组血清高密度脂蛋白胆固醇(high-density lipoprotein cholesterol,HDL-C)水平较低,置入支架明显较长(P<0.05);介入术后血管残余狭窄>20%在再狭窄组中的比例明显升高,且中度狭窄比例高于无狭窄组(P<0.05)。 结论 血清HDL-C、支架长度及支架残余狭窄可能是TA患者支架内再狭窄的影响因素。

     

    Abstract: Objective To study the predictors and reasons for restenosis in patients with Takayasu’s arteritis(TA) after stenting in order to provide evidence for its clinical intervention. Methods Fifty TA patients who underwent stenting in our hospital from January 2000 to August 2011 were included in this study.The patients were divided into restenosis group and non-restenosis group.Their clinical data and vascular angiographic findings were compared.Independent risk factors for restenosis in TA patients were analyzed using logistic regression model. Results The serum HDL-C level was significantly lower and the implanted stent was significantly longer in restenosis group than in non-restenosis group(P<0.05).The proportion of residual stenosis >20% and moderate stenosis was higher in restenosis group than in non-restenosis group(P<0.05). Conclusion Serum HDL-C level,stent length and residual stenosis may be the influencing factors for restenosis in TA patients.

     

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