Abstract:
Objective To analyze the correlation between brachial-ankle pulse wave velocity (baPWV) and left ventricular hypertrophy (LVH) in hypertensive patients.
Methods A total 969 primary hypertensive patients admitted to our hospital from September 2009 to June 2012 were divided into hypertension with LVH group (n=380) and hypertension without LVH group(n=589).Their bilateral baPWV was measured with automatic arteriosclerosis detector and its average value was calculated.
Results The baPWV value was significantly higher in hypertension with LVH group than in hypertension without LVH group (
P< 0.05).Linear correlation analysis showed that the baPW value was positively correlated with the interventricular septal thickness (
r=0.139;
P< 0.01), LV posterior wall thickness (
r=0.124,
P< 0.01), and LV mass index (
r=0.312,
P< 0.01).Multivariate linear regression analysis displayed that the baPWV value was correlated with the interventricular septal thickness (
β=0.125,
P< 0.05), LV posterior wall thickness (
β=0.131,
P< 0.05), and LV mass index (
β=0.027,
P< 0.01) after adjustment of cardiovascular risk factors, such as age, gender, BMI, SBP, DBP, blood glucose, serum cholesterol, LDL cholesterol, HDL cholesterol, triglyceride.
Conclusion baPWV is closely correlated with LVH in hypertensive patients.