Abstract: Objective To study the clinical outcome of radical gastroesophagetomy with small incision in patients with tubular gastroesophageal cancer. Methods Clinical data about 150 gastrogastroesophageal cancer patients who underwent radical gastroesophagetomy with a small incision in our hospital from October 2009 to March 2012 were retrospectively analyzed. The procedure was assessed according to the operation time, intraoperative blood loss, postoperative complications and pulmonary function. Results The radical resection rate of gastroesophageal cancer was 100%. The incision was (13.4±2.8) cm long. The operation time was (213±28) min. The intraoperative blood loss was (340±207.2) ml. The incidence of postoperative complications was 10.5%. The incidence of pulmonary complication was the highest, accounting for 4%. The forced vital capacity and expiratory volume were (2.73±0.85) L and (1.91±0.32) L, respectively, 1 month and 1 second after operation, which were not significantly lower than those before operation (P＞0.05). Conclusion Radical gastroesophagectomy with a small incision is characterized by less traumas, less complications and easy to perform as compared with traditional surgery, but its indications should be strictly taken into consideration.