Abstract: Objective To investigate the awareness of EBM knowledge in authors of Academic Journal of Chinese PLA Medical School and its influencing factors. Methods The awareness of EBM knowledge in 275 authors who submitted papers to Academic Journal of Chinese PLA Medical School from April 2011 to April 2013 and its influencing factors were investigated with questionnaire. Results Of the 275 authors, 38(13.8%) considered that they had a good EBM knowledge, 158(57.5%) considered that EBM was very important in directing clinical research, and 25(9.1%) considered that EBM knowledge was rather frequently used in clinical practice. Multivariate analysis showed that age, academic title, and hospital class were the influencing factors for the awareness of EBM knowledge. Increased age was a favorable factor for the awareness of EBM knowledge(P=0.027), academic title of medical and research series is the beneficial factor for the importance recognition of EBM knowledge(P=0.000), increased age and hospital class were the favorable factors for the use of EBM knowledge(P=0.048, P=0.029). Conclusion Enforced training of EBM knowledge and its application methods in young and junior medical staff and in medical institutions at different levels is the key to improving their awareness of EBM knowledge.