水囊联合不同剂量雌激素用于宫腔粘连辅助治疗的疗效观察

Clinical observation of the combination of Foley catheter and different dosages of estrogen for ancillary treatment of uterine adhesions after adhesiolysis

  • 摘要: 目的 评价Foley尿管水囊联合不同剂量雌激素(戊酸雌二醇,estradiol valerate,E2V)用于宫腔粘连的辅助治疗效果。 方法 选取30例宫腔镜下行宫腔粘连分离术和宫腔留置Foley尿管水囊的患者,其中15例给予雌激素4 mg/d,15例给予雌激素12 mg/d共1个月。所有病例均于术后1个月、3个月进行随访,观察月经恢复情况、内膜厚度增加情况及宫腔形态恢复情况。 结果 两组治疗的有效率分别为60%(9/15)和66.7%(10/15),差异无统计学意义(P> 0.05);两组妊娠率分别为20%(3/15)和46.7%(7/15),总体妊娠率为33.3%(10/30),差异无统计学意义(P> 0.05)。 结论 宫腔镜下宫腔粘连分离术后辅以Foley尿管水囊联合两种剂量雌激素治疗效果无统计学差异。

     

    Abstract: Objective To evaluate the effects of the combination of Foley catheter and different dosages of estrogen (estradiol valerate) on ancillary treatment of uterine adhesion after hysteroscopic adhesiolysis. Methods Thirty patients who underwent hysteroscopic adhesiolysis and then were put an intrauterine balloon of Foley catheter were selected. Fifteen patients were treated with E2V (4 mg/d), and the other ffteen patients were treated with E2V (12 mg/d) for one month. One and three months after the surgery, all cases were followed up to identify the recovery of the menstruation, the thickness of the endometrium and to perform a second look of hysteroscopy. Results The rate of the improvement of clinical symptoms was 60% (9/15) in low dosage group and 66.7% (10/15) in high dosage group, which was of no statistical signifcance (P> 0.05). The total pregnancy rate was 33.3% (10/30), with 20% (3/15) in low dosage group against 46.7% (7/15) in high dosage group, which was of no statistical signifcance (P> 0.05). Conclusion The treatment effect of the combination of Foley catheter and E2V (4 mg/d) is of no statistical signifcance to that of Foley catheter and E2V (12 mg/d).

     

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