Abstract: Objective To detect the changes of left ventricular functions in patients with coronary artery chronic total occlusions（CA CTOs） before and after PCI using two dimensional speckle tracking imaging（2DSTI） and real-time three dimensional echocardiography（RT3DE）. Methods Fifty patients with CA CTOs admitted to the First Affiliated Hospital of Liaoning Medical College were enrolled in our study. All included patients and 30 normal controls underwent standard echocardiography with RT3 DE and 2DSTI to assess the left ventricular ejection fraction（LVEF）, left ventricular end-diastolic volume（LVEDV）, left ventricular end-systolic volume（LVESV）, systolic dyssynchrony index（SDI） and left ventricular global longitudinal strain（LVGLS） before operation and 1 month after operation. Results One month after PCI, LVEF and LVGLS significantly increased（P＜0.05）, while LVEDV, LVESV and SDI significantly decreased（P＜0.05）. However, compared with the control group, each parameter index still did not up to the normal standard（P＜0.05）. The increase of LVGLS and LVEF showed positive correlation（r=0.27, P=0.02）. Conclusion LVEF, LVEDV, LVESV, SDI derived from RT3 DE and LVGLS derived from 2DSTI can evaluate the recovery of the left ventricular function in CA CTOs patients effectively after PCI, which suggests significant improvement of left ventricular function.