Abstract: Objective To analyze helicopter and fighter pilots' disease spectrum in annual checkup from 2009 to 2013 in Air Force Qingdao AM Evaluation and Training Centre, and offer better aviation health care. Methods Health information about 2 023 helicopter and fighter pilots from January 2009 to December 2013 in our centre were collected and the disease spectrum after analyzing the constituent of the main diseases was analyzed. Results The morbidities of ametropia (=5.27, P< 0.05) and elevation of serum single transamination (=7.09, P< 0.01) of helicopter pilots were higher than that of fghter pilots. The morbidities of hyperuricemia=4.40, P< 0.05), cervical spondylosis (=7.40, P< 0.01), hepatic cyst (=3.90，P< 0.05) and lumbar disc herniation4.03, P< 0.05) of fghter pilots were higher than that of helicopter pilots. Digestive diseases, metabolic diseases and orthopedics diseases of the two types of airplane accounted for more than 80% of the total. Conclusion More attention has to be paid on metabolic disease, which shows high-incidence disease in these two types of airplane. Individual prevention and treatment has to be put into effect for the different disease spectrum of different types of airplane.