Abstract: Prostate cancer (PC) is a common male malignant tumor with increasing morbidity and mortality in China. With the development of technologies of accurate radiotherapy, external beam radiation therapy (EBRT) has become one of the radical therapeutic methods for localized PC. Due to the special biological characteristics of PC, hypofractionated-high-dose radiotherapy can achieve better therapeutic results in clinic. The current state of hypofractionated-high-dose radiotherapy in PC is summarized in this review.