Abstract: Objective To assess the value of intraoperative nerve monitoring in reoperation for differentiated thyroid carcinoma. Methods Clinical data about 92 patients who underwent differentiated thyroid carcinoma reoperation with intraoperative nerve monitoring from October 2012 to October 2014 in the department of general surgery of Chinese PLA General Hospital were retrospectively analyzed. Results All operations were successfully completed without any symptoms of postoperative bleeding, bucking or hand and foot numbness. The recurrent laryngeal nerve signal in 3 cases were temporarily abnormal. Two cases were found to have temporary recurrent laryngeal nerve injures and no permanent recurrent laryngeal nerve injury was found. Conclusion Intraoperative nerve monitoring can assist surgeons in finding recurrent laryngeal nerve quickly during operation and reducing rate of recurrent laryngeal nerve injury, which is worthy of being applied in surgery widely.