Abstract: Objective To explore the clinical effect of renal transplantation from donation after cardiac death (DCD) in single center. Methods Follow-up data about 21 cases with DCD renal transplantation in The 309th Hospital of Chinese PLA from April 2012 to September 2014 were retrospectively analyzed. Results Two of fourteen DCD donors were abandoned due to long warm ischaemia time, another 12 cases donated 24 kidneys and 21 cases underwent single kidney transplantation in our hospital. DCD recipients were followed up for 1 to 28 months. Of the 21 cases, primary non-function (PNF) only occurred in one case (4.8%) and delayed graft function (DGF) in 8 (38.1%) recipients, acute rejection (AR) in 4 (19.1%) recipients. Two (9.5%) recipients lost their graft. One case had nephrectomy due to the rupture of graft and one case had nephrectomy due to PNF. Nineteen recipients recovered to normal renal function. But two (9.5%) recipients died with normal renal function, of which, one was acute pneumonia and one was traffic accident. The actuarial survival rates of recipients and grafts at 6, 12, 18, 24 months after renal transplantation were 95.2%, 95.2%, 90.5%, 90.5%, and 85.7%, 85.7%, 80.9%, 80.9%, respectively. Conclusion Chinese category Ⅲcardiac death transplant recipients have good short term patient/kidney survival rate and is a potential method to relieve the shortage of donative organs.