内镜治疗自身免疫性肝硬化与乙肝肝硬化合并食管胃静脉曲张后复发时间比较

申少华; 刘迎娣; 王娟; 高伟; 吴文涛; 孙国辉; 杨竞; 孙刚; 孙潇; 李萌

doi:10.3969/j.issn.2095-5227.2015.11.004

内镜治疗自身免疫性肝硬化与乙肝肝硬化合并食管胃静脉曲张后复发时间比较

Recurrence time of gastroesophageal varices after endoscopic treatment in patients with autoimmune cirrhosis or hepatitis B cirrhosis

摘要

摘要: 目的探讨自身免疫性肝硬化与乙型肝炎肝硬化合并食管胃静脉曲张内镜治疗后复发的临床特点。方法回顾性分析2006 - 2013年在解放军总医院消化内科行内镜下治疗的20例自身免疫性肝硬化合并食管胃静脉曲张患者治疗后复发的临床特点，并与同期住院的43例乙肝肝硬化合并食管胃静脉曲张患者的第1次内镜下治疗次数及治疗后复发时间进行对比。结果自身免疫性肝硬化和乙肝肝硬化患者第1次内镜治疗平均次数分别为2.10±1.25次和2.93±1.20次，两者差异有统计学意义(P< 0.05)，而且自身免疫性肝硬化复发时间较乙肝肝硬化提前(P< 0.05)，分别为0.70±0.44年和1.22±0.97年。结论内镜治疗后自身免疫性肝硬化较乙型肝炎肝硬化更早复发。

Abstract: Objective To investigate the recurrence time of gastroesophageal varices after endoscopic treatment in patients with autoimmune cirrhosis or hepatitis B cirrhosis. Methods Clinical features of 20 patients with gastroesophageal varices with autoimmune cirrhosis who were conducted with endoscopic treatment in our hospital from 2006 to 2013 were retrospectively analyzed, and their mean number for first endoscopic treatment and recurrence time after treatment were compared with 43 patients with hepatitis B cirrhosis in our hospital during the same period. Results Compared with patients with hepatitis B cirrhosis, the mean number of first endoscopic treatment in patients with autoimmune cirrhosis was significantly less (2.93±1.20) vs (2.10±1.25), P< 0.05, and the recurrence time of autoimmune cirrhosis was significantly earlier (0.70±0.44) vs (1.22±0.97), P< 0.05. Conclusion Compared with patients with hepatitis B cirrhosis, patients with autoimmune cirrhosis relapse earlier after endoscopic treatment.

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