Abstract: Objective To investigate the feasibility of laparoscopic treatment for Mirizzi syndrome and determine associated risks and complications of this technique. Methods PubMed, EMBASE, Web of Science, Wanfang, CNKI and cqvip databases were searched from January 2000 to June 2015 for related literatures.Four patients with Mirizzi syndrome treated by laparoscopy were enrolled in this study, their preoperative diagnosis rates, conversion laparotomy rate, complication rate and reoperation data were screened and analyzed systematically. Results Of the 206 studies, 26 eligible studies were identified.The conversion laparotomy, complication, and reoperation rates were 26%, 6.8% and 1.1%, respectively.There were no significant differences in the incidence of reoperation(P＞ 0.05).However, compared with patients in group with low preoperative diagnosis rates, the conversion laparotomy and complication rate of group with high MS diagnosis rate were significantly lower(P＜0.05).Compared to patients with type Ⅱ Mirizzi syndrome, patients with type Ⅰ Mirizzi syndrome had a significantly lower risk for conversion and procedurerelated complications(P＜0.05). Conclusion The laparoscopic treatment for type Ⅰ Mirizzi syndrome can be recommended as a standard procedure, however, it is not fit for patients with type Ⅱ Mirizzi syndrome.There has a correlation between the increase of preoperative diagnosis rates and the decrease of conversion laparotomy and complication rate.