Abstract: Human adipose mesenchymal stem cells(hADMSCs)are regenerative and multi-differentiation potential stem cell.Previous studies have demonstrated that hADMSCs transplantation can effectively promote myocardial regeneration and angiogenesis after myocardial infarction, by improving the heart function and ventricle remolding remarkably.This review introduces the physical characteristics and reparative function of hADMSCs, which derives from different sources.Furthermore, the application of hADMSCs for experiment researches and clinical trials are also summarized in this article, in order to provide fundamental basis for their clinical use.