Abstract:
Objective To discuss the kinds of common allergens in Beijing area and its relationship between different genders, ages and diseases.
Methods From June 2013 to March 2015, the patch test results of 1 484 patients with allergic diseases in Chinese PLA General Hospital were analyzed and grouped by gender, age and the types of dermatitis.
Results Of the 1 484 cases, the total positive rate was 45.4%; In 568 male cases, the positive rate was 42.8%; In 916 female cases, the positive rate was 46.9%, with no statistically significant difference. The most common types of sensitization compounds in Beijing area were nickel sulfate, cobalt chloride and potassium dichromate. Among different age groups, the total positive rate of cobalt chloride (
P=0.031), para-phenylene diamine matrix (
P=0.012), potassium dichromate (
P=0.028), nickel sulfate (
P=0.003) had statistically significant difference. Among different groups of diseases, the total positive rate of nickel sulfate (
P=0.01), Cl+Me- different thiazole (calzone CG) (
P=0.008) also had statistically significant difference.
Conclusion Patch test can help patients identify allergens, which can contribute to the prevention and control of the diseases; For example, cobalt chloride has a higher positive rate among adult groups, while ethylenediamine dihydrochloride has a higher positive rate in eczema patients. Meanwhile, as a noninvasiveness and safety method, patch test can probably contribute to the diagnosis of dermatitis.