Abstract: Objective To investigate the clinical efficacy of percutaneous endoscopic lumbardiscectomy (PELD) for adolescent lumbardisc herniation. Methods Medical records of 18 adolescent patients with LDH (lumbardisc herniation) from November 2008 to April 2012 in Chinese PLA General Hospital, including 11 males and 7 females, with an average age of 15.9 years old (14-18 years old), were retrospectively reviewed. The clinical signs and radiographic materials were evaluated before surgery. The visual analog scale (VAS) scores for low back pain and leg pain, Oswestrydisability Index (ODI) scores were recorded and compared at the follow time points: before surgery, 1day, 1 month, 6 months, 1 year after operation. The clinical outcomes at the final follow-up were assessed by modified Macnab criteria. Results The average operationduration was 45 min (ranged from 30 min to 65 min), the mean length of incision was 7 mm (ranged from 6 mm to 8 mm), and the mean intraoperative blood loss was 5 ml (ranged from 3 ml to 10 ml). No complication such as infection or neurovascular injury occurred. The average follow-upduration was 54.5 months ranging from 33-76 months. The VAS score of low back pain was 5.22±1.06 points preoperatively, which reduced to 0.67±0.77 points at the latest follow-up (P< 0.05).The VAS score of leg pain was 7.78±0.73 points preoperatively, which reduced to 0.78±0.55 points at the latest follow-up (P< 0.05). The ODI score was 65.6±7.24 points preoperatively, which reduced to 3.50±3.12 points at the latest follow-up (P< 0.05). At the last follow-up, the scores of the modified Macnab criteria were excellent in 15 patients and good in 3 patients. Conclusion PELD is safe and effective, which provides a new choice for adolescent lumbardisc herniation.