Abstract: Objective To analyze the clinical efficacy of percutaneous renal artery stenting (PTARS) on patients with atherosclerotic renal artery stenosis (ARAS). Methods The study included 273 patients with unilateral or bilateral renal artery stenosis≥70% who were hospitalized in our hospital from January 2008 to April 2015. Renal artery stenting was performed through femoral artery or radial artery. The changes of blood pressure, drugs and renal function were observed in a 6-month follow-up. Results Of the 273 cases, as for hypertension, 91 patients (33.3%) were cured, 159 cases (58.2%) were improved, and invalid was found in 23 cases (8.5%). Six months after stenting, the blood pressure of patients were significantly lower than preoperative stage systolic pressure: (137±17) mmHg vs (163±19) mmHg, diastolic pressure: (84±8) mmHg vs (93±12) mmHg, P< 0.05, the categories of antihypertensive drugs were significantly less than preoperative (2.0±0.4) vs (2.7±1.3), P< 0.05, while the serum creatinine and glomerular filtration rate did not significantly changed (121.3±60.5)μmol/L vs (122.7±61.3)μmol/L, P> 0.05; (70.2±19.5) ml/min vs (70.5±18.8) ml/min, P> 0.05. Conclusion Stent implantation is effective in the treatment of ARAS, which decreases the blood pressure of patients and makes it easier to be controlled, but it does not have any exactly protective effect on renal function.