Abstract: Objective To observe the curative effects of low-intensity focused ultrasound combined with semi-conductor laser for patients with plantar fasciitis. Methods Clinical data about 66 patients with plantar fasciitis admitted to our department from August 2014 to August 2015 were collected.All patients were randomly divided into two groups: treatment group (n=33) and control group (n=33).Patients in treatment group received low-intensity focused ultrasound combined with semi-conductor laser, and patients in control group received semi-conductor laser only for 3 therapeutics courses. All patients were followed up for 2 months. Visual analogue scale (VAS) score and the effectiveness rate of the two groups were compared. Results All patients were followed up with no recurrence. Statistical difference was found in VAS scores of two groups between pre- and post-treatment (8.2±1.1) vs (1.7±0.9), (8.1±1.0) vs (2.3±1.2), P＜0.05. VAS score in treatment group was significantly lower than control group after treatment (1.7±0.9) vs (2.3±1.2), P＜0.05, and the effectiveness rate of treatment group was significantly higher than that of control group (96.97% vs 87.88%, P＜0.05). Conclusion The low-intensity focused ultrasound combined with semi-conductor laser for the plantar fasciitis is a reliable method, which is worthy to be popularized.