Abstract: Colorectal cancer (CRC) is one of the most common malignant tumors. Early screening is the key measure to reduce the morbidity and mortality of colorectal cancer and improve its prognosis. Risk assessment model can be used to stratify the risk population in order to provide different screening programs. A good risk assessment model can effectively improve the detection rate of CRC and reduce unnecessary waste of medical resources. Here we will review the risk assessment models for CRC, and briefly introduce their practicality and efficiency.