Abstract: Objective To compare the effectiveness of vaginal or laparoscopic surgery in the treatment for cervical myoma. Methods A total of 89 cases with cervical myoma in our hospital during June 2011 to June 2016 were selected.All cases were divided into observation group (vaginal myomectomy) and control group (laparoscopic myomectomy).The clinical data and operative indexes were compared between the two groups. Results There was no signi ficant difference between the two groups in mean age, maximum diameter of myoma, type of myoma, clinical symptoms and hysterectomy option.The operating time(45.6±19.3 min vs 62.0±27.1 min, P=0.001) and blood loss (53.6±18.8 ml vs 64.2±25.9 ml, P=0.029) in observation group were less than those in control group with statistically signi ficant differences.There was no signi ficant difference in average hospitalization days (5.7±1.3 days vs 5.2±1.1 days) and complication rates (17.0% vs 26.2%) between the two groups (P＞ 0.05, respectively). Conclusion Compared with laparoscopic myomectomy, vaginal myomectomy is more effective and safe for patients with cervical myoma.