Abstract: Objective To study the clinical outcomes of different surgical methods in treatment of open-angle glaucoma complicated with cataract. Methods Seventy-eight cases with open-angle glaucoma complicated with cataract were enrolled in this study in the first Affiliated Hospital of Harbin Medical University from January 2014 to May 2015. The patients were randomly divided into two groups: group A (39 cases, 40 eyes) and group B (39 cases, 40 eyes). Patients in group A underwent phacoemulsification with intraocular lens implantation and trabeculectomy, while group B underwent small incision cataract extraction with intraocular lens implantation and trabeculectomy. The visual acuity, intraocular pressure at 1 week and 1 month after surgery, and the incidence of operative complications within 1 month after surgery were compared between the two groups. Results The incidence of postoperative anterior chamber inflammation was significantly lower in group A than that of group B (10.0% vs 22.5%, P＜ 0.05), while the incidence of other complications was similar in the two groups (P＞ 0.05). The postoperative visual acuity and intraocular pressure at 1 week and 1 month after surgery improved significantly after surgery in both two groups. But there was no significant difference in postoperative visual acuity and intraocular pressure levels between two groups (P＞ 0.05). Conclusion Both the two surgery methods can effectively improve postoperative visual acuity and ocular pressure in patients with open-angle glaucoma and cataract. But, there are less complications in patients undergoing phacoemulsification with intraocular lens implantation and trabeculectomy.