Abstract: Objective To evaluate macular degeneration by B-scan ultrasonography before cataract surgery and examine its diagnostic accuracy comparing with optical coherence tomography (OCT)． Methods It was a prospective study． Totally 228 cases (228 eyes) with cataract who underwent phacoemulsification and foldable lens implantation in Chinese PLA General Hospital from January 2014 to March 2015 were included in this study． Preoperative examinations (the morphology of the macular) were performed in 228 eyes using OCT and B-scan ultrasonography, respectively． All patients were divided into macular degeneration group and nonmacular degeneration group according to the results of B-scan ultrasonography． Then the results of ultrasonography and the diagnosis of OCT in the frequency domain were analyzed and compared, and the best corrected visual acuity of the two groups was compared before and at 1 week after cataract surgery． Results Before surgery, 67 cases were diagnosed as macular degeneration and 161 cases without macular degeneration by ultrasonography． Macular degeneration was diagnosed in 67 cases by OCT in macular degeneration group． For 161 cases in non-macular degeneration group, macular degeneration was diagnosed in 12 cases by OCT． The concordance rate between two examinations for macular degeneration was 94．7% (216/228), and the preoperative ultrasound diagnosis was highly consistent with OCT (Kappa=0．879)． Before surgery, the best corrected visual acuity (BCVA) of the patients in macular degeneration group was 0．21±0．15, which was not significantly different with 0．23±0．17 in the patients without macular degeneration (t=0．443, P=0．443)． A week after the surgery, BCVA in patients of macular degeneration group was significantly lower than that in patients without macular degeneration group (0．31±0．18 vs 0．87±0．23, P< 0．01)． Conclusion The accuracy of B-scan ultrasonography in diagnosis of macular degeneration is high, which can be used to predict the correct vision before cataract surgery with important clinical significance．