Abstract: The infant virome refers to the sum of all viruses, virus-like particles, and their genetic information in the gut. The formation of gut virus in infants begins with the birth of the baby and gradually matures under the influence of factors such as birth pattern, feeding pattern, diet, and environment. In addition, the gut virome can directly or indirectly regulate host immunity, microbial metabolism and nutrition, and the formation of mucosal barriers affect the health of the host. However, the current research progress in infant's virome is relatively rare. It is necessary to further expand growth and the virome database, explore the correlation between the virome and other microbial populations, and analyze its role in the development of infants.