胸椎管狭窄症的研究现状与治疗进展

Research and treatment progress in thoracic spinal stenosis

  • 摘要: 胸椎管狭窄症(thoracic spinal stenosis,TSS)发病机制不详,致病原因多样,包括遗传、局部力学因素、老年性退变、内分泌因素及微量元素代谢异常等。TSS常同时存在胸椎间盘突出、后纵韧带骨化及黄韧带骨化等多种病理变化,且患者常同时伴颈、腰椎疾患,病变累及的节段范围不定,可仅1节段受累,也可发生于全胸椎,所以其临床表现复杂多样,极易误诊。手术治疗是其唯一有效的方法,若不及时手术解除致压因素,则会造成无法挽救的后果。手术损伤脊髓的风险较大,术后极易出现严重并发症。本文对该病病因、诊断、治疗方案及预后等方面的研究现状做一综述。

     

    Abstract: The pathogenesis of thoracic spinal stenosis (TSS) is unknown, and the causes of TSS are varied, including genetic, local mechanical factors, age-related degeneration, endocrinic factor and metabolic abnormalities of trace element and so on. TSS often contains both posterior longitudinal ligament ossification and thoracic disc herniation, and a variety of pathological changes such as yellow ligament ossification. Meanwhile it is frequently complicated with cervical, lumbar spine diseases. The section of lesion involved is uncertain, maybe one segment, or the whole thoracic vertebra, so that the clinical manifestations are complex and varied, leading to frequent misdiagnosis. Surgical treatment is the only effective treatment. If the pressure factors can not be removed in time, it will cause irreversible consequences. The risk of surgical injury to the spinal cord is very high, and severe complications are common seen. This article reviews the current research and treatment progress of this disease.

     

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