Abstract: Objective To investigate the protective effects of high expression of neuroglobin induced by Hemin on motor functions of rats with spinal cord injuries. Methods Healthy male SD rats were randomly divided into three groups, control group(sham operation group), operation group and Hemin treatment group(intraperitoneal injection of Hemin solutions after molding). Rat hindlimb function BBB scale was used to evaluate the difference in motor functions among rats from the three groups at 1 d, 3 d, 7 d,14 d, 28 d, 56 d after experiment. Results The results of Ngb immunohistochemistry of rats spinal cord tissue showed that at the early and middle stages after operation, the number of Ngb positive cells was highest in the Hemein treatment group, followed by the operation group and the lowest in the control group. Postoperative BBB score was highest in the control group at each time point, and lowest in operation group. Hemin treatment group had the fastest recovery rate. Conclusion Hemin treatment improves the motor functions of rats with spinal cord injuries and accelerates the motor function recovery after spinal cord injuries.