Abstract: Objective To explore the effect of enteral nutrition via nasojejunal approach versus percutaneous endoscopic jejunostomy approach after surgery in patients with typeⅡadenocarcinoma of esophagogastric junction (AEG). Methods Eighty-four patients who underwent total laparoscopic transabdominal and transdiaphragmatic gastrectomy in the sixth medical center of Chinese PLA General Hospital from January 2015 to January 2019 were selected,and they were randomly divided into percutaneous jejunostomy group (observation group,n=42) and nasojejunal group (control group,n=42).The time of tube placement,nutritional status,immune function,level of postoperative satisfaction,incidence of perioperative complications and following-up of the two groups were compared. Results There was no statistically significant difference in the time of placing tube,nutritional status and immune function between the two groups.The level of postoperative satisfaction of the observation group was significantly higher than that of the control group (4.8±0.4 vs 3.6±0.8,P=0.000).The incidence of short-term postoperative complications of observation group was significantly lower than that of control group (14.2% vs 33.3%,P=0.040). Conclusion For typeⅡAEG patients after surgery,the percutaneous jejunostomy should be used with priority to supply nutrition so that they could recover in short time.