Abstract: Objective To analyze fundus and fluorescein angiography (FAG) findings and characteristics of different stages of nonarteritic anterior ischemic optic neuropathy (NAION). Methods A retrospective analysis was performed in 80 patients (113 eyes) with clinically diagnosed non-arterial anterior ischemic optic neuropathy in our center from 2012 to 2019,and the patients were classified into group A (less than 1 month),B (1-6 months),and C (more than 6 months) according to the disease course.The fundus photography and fluorescence angiography images of the three groups were observed and compared. Results In group A,fundus photography showed 34 eyes (94.4%) had optic disc edema,27 eyes (75.0%) had hemorrhage around the optic disc;Fluorescence angiography showed 26 eyes (72.2%) had delayed optic disc filling,and hyperfluorescent staining in quadrant in early phase.In group B,15 eyes (55.5%) showed disc edema and hemorrhage around disc in fundus photography,and quadrant distribution of fluorescence in disc was found in early stage of FAG.In group C,49 eyes (98.0%) had optic nerve atrophy,and 46 eyes (92.0%) demonstrated deep-layer fluorescence filling defect of disc and persistent hypofluorescence in the late stage of FAG. Conclusion NAION mainlymanifests as optic disc edema accompanied by peripheral hemorrhage and exudation,and optic disc quadrant fluorescence distribution in early stage;decreased hemorrhage and exudation,and persistent hypofluorescencee of the optic disc in the intermediate stage;optic nerve atrophy,and changes in filling of retinal artery and vein in late stage.FAG can provide strong evidence for the diagnosis,staging and differentiation of NAION.