Abstract: Objective To support clinical research by extracting structured information from more than 10 000 breast cancer pathological reports of Chinese PLA General Hospital. Methods We collected 10 590 pathological reports of breast cancer from 2005 to 2017 in Chinese PLA General Hospital.Combined the needs of clinical scientific research and expert experience,we constructed the index dictionary and extraction rules,and extracted the information from the pathological report by the extraction method of rule-based pattern matching. Results We got the text structured indexes and their values which were needed in the clinical scientific research from the breast cancer pathological reports by our method.According to the effect evaluation to 200 random pathological reports,the recall rate and accuracy of indexes obtained by the extraction method based on pattern matching were both higher than 90%. Conclusion The information extraction method based on rule-based pattern matching is feasible and can quickly extract information from the breast cancer pathological reports.