Abstract: Objective To investigate the psychological health status of the first batch of military medical teams assisting Wuhan for COVID-19 and its influencing factors. Methods Totally 93 nurses (4 males,89 females) who participated in the first batch of medical teams assisting Hubei to fight COVID-19 from a teaching hospital and 90 first-line nurses clinical (5 males,85 females) who did not go to Wuhan for support during the same period were investigated by symptom checklist 90 (SCL-90).The investigation was completed on the 10th day (February 3,2020) when the medical team arrived in Wuhan,the psychological symptoms were compared between the two groups and their influencing factors were analyzed. Results The score of anxiety dimension (1.49±0.37) of the front-line support group was significantly higher than that of the military norm (1.37±0.48),the national norm (1.39±0.43) and the in-hospital control group (1.39±0.31) (all P<0.05),and the score of obsessive dimension (1.76±0.43) of the front-line support group was significantly higher than that of the military norm (1.56±0.54) and the national norm (1.62±0.58) (all P<0.01).Multivariate analysis verified that education level was a protective factor influencing the occurrence of obsessive symptoms (OR=0.034,P=0.049). Conclusion The psychological anxiety and obsessive symptoms of the first batch of support nurses are obvious.The pre-job training with clear focus,various psychological interventions,extensive psychological support and humanistic care should be provided by the institution.