人工智能对肝癌患者预后预测的研究进展

Research advances in artificial intelligence in predicting prognosis of patients with hepatocellular carcinoma

  • 摘要: 肝细胞癌(hepatocellular carcinoma,HCC)是发病率和死亡率很高的肝恶性肿瘤,手术切除或肝移植是治疗早期肝癌的最有效方法,然而高复发率和转移率仍导致术后长期生存率较低。肝癌预后的预测常联合使用甲胎蛋白、超声、电子计算机断层扫描和磁共振成像。近年来,人工智能在肝癌治疗效果评估和预后预测方面表现出良好的性能。本文对人工智能在肝癌手术切除、肝动脉化疗栓塞、射频消融、肝移植、靶向治疗、放射治疗、综合治疗等方面的应用进展进行综述。

     

    Abstract: Hepatocellular carcinoma (HCC) is a kind of liver malignant tumor with high morbidity and mortality.Surgical resection or liver transplantation are the most effective method for the treatment of early liver cancer.However,the postoperative recurrence and metastasis rate are very high,which seriously affects patients' prognosis.Alpha-fetoprotein (AFP) ultrasound,electronic computed tomography (CT) and magnetic resonance imaging (MRI) are often jointly used to predict the prognosis of HCC patients.Recently,artificial intelligence (AI) has shown good performance in evaluating the treatment effect and prognosis prediction of liver cancer.This article reviews the application progress of artificial intelligence in prognosis predicting after surgical resection of hepatocellular carcinoma,hepatic arterial chemoembolization,radiofrequency ablation,liver transplantation,targeted therapy,radiotherapy and comprehensive therapy.

     

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