Abstract:
Background Microvascular obstruction (MVO) increases the risk of adverse events in patients with acute ST-segment elevation myocardial infarction (STEMI) after percutaneous coronary intervention (PCI).
Objective To investigate the factors associated with coronary MVO in patients with ST-segment elevation infraction after PCI.
Methods A retrospective analysis was conducted in 125 patients with acute ST-segment elevation infraction who underwent primary percutaneous coronary intervention (PPCI) in the department of cardiology medicine, Jiangnan Hospital, and the department of cardiology medicine, the First Medical Center of Chinese PLA General Hospital. There were 109 males and 16 females, with an average age of (56.91±10.85) years old. According to the occurrence of MVO during postoperative periods, the patients were divided into MVO group (n=54) and non-MVO group (n=71). Logistic regression was used to analyze the factors associated with microvascular obstruction in STEMI patients after PCI.
Results Multivariate logistic regression showed that preoperative level of white blood cell (OR: 1.157, 95% CI: 1.008-1.328, P=0.039), the number of stents implanted (OR: 1.916, 95% CI: 1.069-3.436, P=0.029) and myocardial infarct size>20% (OR: 6.302, 95% CI: 2.386-16.644, P<0.001) were independently associated with the occurrence of MVO in acute STEMI patients after PCI.
Conclusion Preoperative level of white blood cell, the number of stents implanted and myocardial infarct size>20% can predict the occurrence of MVO in STEMI patients after PCI. Monitoring these factors in the early stage can initially assess the risk of developing MVO in STEMI patients who underwent PCI.
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