Abstract: Objective To study the correlation between squamous cell carcinoma antigen（SCC-Ag） and cervical cancer stage and prognosisMethods One hundred and sixty-four patients with cervical cancer admitted to our hospital in 2006-2009 were enrolled in this study.Correlation between positive SCC-Ag rate and cervical cancer stage and types was retrospectively analyzed before and after treatmentResults The positive SCC-Ag rate was obviously higher in cervical squamous cell carcinoma patients.The more advanced the stage of cervical cancer was,the higher the positive SCC-Ag rate was.The positive SCC-Ag rate was obviously lower after operation than before operation（P＜0.05）.The positive SCC-Ag rate was not significantly increased in cervical adenocarcinoma patientsConclusion The positive SCC-Ag rate is positively correlated with cervical squamous carcinoma stage.The serum SCC-Ag level can be used as a severity index of cervical squamous carcinoma and its therapeutic effect.