饮食饮酒及肥胖对无症状高尿酸血症发生痛风的影响

Effect of diet,drinking and obesity on development of gout in patients with asymptomatic hyperuricemia

  • 摘要: 目的 调查我院体检人群中痛风及无症状高尿酸血症的基本情况,分析饮食、饮酒、肥胖等因素对其的影响,从而筛选无症状高尿酸血症人群发生痛风的危险因素。 方法 对2010年5-8月在我院体检的1 209例人员进行调查,其中34例确诊的痛风患者为痛风组,63例无症状高尿酸血症者为高尿酸组,血尿酸正常人群中抽取118例为对照组,探讨饮食、饮酒、肥胖等方面的危险性。 结果 蔬菜、奶类、酒精摄入量和腰围在痛风组、高尿酸组和对照组间比较差异有统计学意义(P<0.05);痛风组和高尿酸组在酒精摄入量、腰围比较差异有统计学意义(P<0.05)。对酒精摄入量、腰围进行回归分析腰围OR为0.090,P为0.022<0.05;酒精摄入量OR为0.646,P为0.019<0.05。 结论 中心性肥胖、酒精摄入量是高尿酸血症人群发生痛风的危险因素。

     

    Abstract: Objective To analyze the effect of diet,drinking and obesity on gout in patients with asymptomatic hyperuricemia by investigating their general condition. Methods Among the 1 209 persons who underwent physical and health examination in our hospital in May-August 2010,34 who were diagnosed as gout served as a gout group,63 with asymptomatic hyperuricemia served as a hyperuricemia group,and 118 with normal uric acid served as a control group.Effect of diet,drinking and obesity on gout was studied. Results The intake of vegetables,dairy and alcohol,and the waistline were significantly different among the 3 groups(P<0.05).The alcohol intake and waistline were significantly different between the gout and hyperuricemia groups(P<0.05).Logistic regression analysis showed that the OR was 0.090 for waistline and 0.646 for alcohol intake(P<0.05). Conclusion Central obesity and alcohol intake are the risk factors for gout in patients with asymptomatic hyperuricemia.

     

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