Abstract: Objective To study the correlation between risk factors for coronary artery disease and SYNTAX score,and analyze the prediction of mid-and long-term outcomes in aged patients receiving percutaneous coronary intervention（PCI） with SYNTAX score. Methods One hundred and forty-five patients aged over 75 years were divided into low score（0-22） group（n=84）,medium score（23-32） group（n=32）,and high score（≥33） group（n=29） according to their SYNTAX scores.Their data were retrospectively analyzed. Results The fasting blood glucose（FBG） and serum creatinine levels and the SYNTAX scores were significantly higher in the patients after PCI than before PCI.Of the 145 patients,113 were followed up for≥6 months after PCI.The incidence of major adverse cardiac and cerebrovascular events（MACCE） was 10.8%,12.5%,and 25.0% respectively in the 3 groups（P=0.224）.The recurrent incidence of angina pectoris was 32.3%,29.2%,and 50.0% respectively in the 3 groups（P=0.233）.The readmission rate was 23.1%,20.8%,and 41.7% respectively for the patients in the 3 groups（P=0.164）.The mortality was 6.2%,8.3%,and 12.5% respectively in the 3 groups（P=0.616）. Conclusion SYNTAX scores are not significantly correlated with the mid-and long-term outcomes in aged patients.