Abstract:
Objective: To evaluate the diagnostic value of
67Ga citrate scintigraphy for lung sarcoidosis and its clinical application. Methods: A total of 72 patients(66 patients with lung sarcoidosis and 6 patients without lung sarcoidosis but with tuberculosis)were included in this study.Their
67Ga citrate scintigraphy,chest X-ray film and CT as well as their pathological data were analyzed retrospectively. Results: The diagnostic accuracy of
67Ga citrate planar image and X-ray film combined with CT was 83.3%(55/66)and 78.8%(52/66),respectively.No significantly difference was found between the two methods(P=0.656 8).Pathological examination was performed for 12 patients with lung sarcoidosis,but the results were different.The diagnostic accuracy of
67Ga citrate planar image and X-ray film combined with CT was 91.7%(11/12)and 33.3%(4/12),respectively.A significantly difference was found between the two methods(P=0.011 4).Pathological examination could not differentiate lung sarcoidosis from tuberculosis in 4 patients,which could not be definitely diagnosed by X-ray and CT.Three of the four patients were diagnosed having lung sarcoidosis by
67Ga citrate planar image according to the pattern of"Panda Face"and the Greek letter lambda located in bilateral hilar lymph nodes,the remaining one without lung sarcoidosis was diagnosed having lung tuberculosis. Conclusion:
67Ga scintigraphy can accurately diagnose lung sarcoidosis in patients with lung tuberculosis.