Abstract: Objective To study the clinical outcome of tendon graft fixation in anterior cruciate ligament（ACL） reconstruction with cortical press-fit bolt（CPB）. Methods The femoral end was fixed with Endobutton+CPB,ACL was reconstructed by fixing tibia with Rigidfix from January 2010 and December 2010 in 17 patients（14 males and 3 females） at the age of 28.6 years（range 15-49 years）.The forward shift of tibia was measured with Rolimeter and the knee function was assessed using the Lysholm scoring system before and after operation.The patients received X-ray and MRI examination after operation. Results The patients were followed up for 6.9 months（range 3-13 months） during which no infection and complications of nerve and blood vessels occurred.X-ray showed that CPB was replaced by creeping fibers 3 months after operation.Significant differences were found in forward shift of tibia before and after operation（P＜0.01）.However,no significant difference was observed in forward shift of tibia between the affected and healthy knees.The preoperative Lysholm score was 31.1±6.3 before operation and 85.2±6.9 after operation（P＜0.001）.The total excellent and good rate was 88.2%. Conclusion CPB fixation can meet the physiological demand of ACL reconstruction with a good histocompatibility.