早期经鼻气管插管对高血压脑出血患者微创治疗后肺部感染的影响
Effect of early nasal endotracheal intubation on pulmonary infection of patients with cerebral hemorrhage due to hypertension after minimally invasive surgery
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摘要: 目的 研究早期经鼻气管插管对高血压脑出血患者微创治疗术后肺部感染发生率、ICU治疗时间的影响。方法 选取58例2007年9月-2009年5月间于我院急诊科就诊并拟行微创治疗的高血压幕上型脑出血患者。根据GCS评分分层后进行随机分组,处理组于就诊时予以早期经鼻气管插管经人工鼻吸氧,对照组予以鼻导管或面罩吸氧,观察术后72h肺炎并发症发生率及ICU治疗时间,研究数据选取Fisher确切概率法及成组t检验方法进行统计分析。结果 不管在GCS评分13~15分或6~12分的高血压脑出血患者中,早期插管组与对照组在术后肺炎发生率方面的差异无统计学意义(GCS13~15:21.4% vs35.7%,P=0.6776;GCS6~12:60% vs80%,P=0.2678),但在ICU治疗时间方面早期插管组较对照组明显缩短,两者间差异具有显著统计学意义(GCS13~15:4.9dvs6.9d;GCS6~12:8.2dvs10.3d,P<0.01)。结论 对于高血压脑出血拟行微创治疗的患者行早期经鼻气管插管可明显减轻术后肺部并发症,减少ICU治疗时间,减轻患者经济负担,促进康复。Abstract: Objective To study the effect of early nasal endotracheal intubation on pulmonary infection and stay time of patients with cerebral hemorrhage due to hypertension in ICU after minimally invasive surgery. Methods Fifty-eight patients diagnosed as cerebral hemorrhage due to hypertension in our department were randomly divided into control group and treatment group according to their GCS scores. Patients in the treatment group underwent early nasal endotracheal intubation and had oxygen inhalation through the nose. Patients in the control group had oxygen inhalation through a nasal tube or face mask. Pneumonia and its complication and stay time in ICU were observed 72h after minimally invasive surgery for cerebral hemorrhage and analyzed by Fisher test and t-test. Results The incidence rate of pneumonia was 21.4% in treatment group after early nasal endotracheal intubation and 35.7% in control group, while it was 60% in treatment group 72h after minimally invasive surgery and 80% in the control group (P>0.05). However, the stay time of patients in the treatment group in ICU was obviously shorter than that of those in the control group (P<0.01). Conclusion Early nasal endotracheal intubation can alleviate the pulmonary complications, shorten the stay time in ICU, lessen the cost and promote the recovery of patients with cerebral hemorrhage due to hypertension after minimally invasive surgery.
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