血管内氧合器的研制及其仿生学特点

Fabrication of the intravascular oxygenator and exploration of its bionical characteristics

摘要: 目的：探索血管内氧合器的氧合机制，改进氧合器的气体交换效率。方法：采用国产聚丙烯中空纤维，自行设计，研制出一种血管内氧合器。对氧合器进行了动物实验研究。结果：应用血管内氧合器后，能部分改善缺氧及高碳酸血症动物的动脉血气指标，提高动脉血氧分压4.06kPa（P＜0.01），降低动脉血二氧化碳分压1.99kPa（P＞0.05）。并从仿生学角度进行了分析。结论：可以仿造鸟和鱼类的肺部结构改良血管内氧合器

Abstract: Objective: In order to study the oxygenation mechanism of intravascular oxygenator（IVOX） and improve its practical efficiency Methods: A new IVOX was fabricated using polypropylene hollow fiber membrane and its efficacy was chacked on 9 experimental dogs Results: In vivo experimental testing of IVOX, arterial blood gas was improved in acute hypoxic and hypercapnic dogs The IVOX could increase PaO₂ 4.06 kPa（P＜0.01）,and decrease PaCO₂ 1.99 kPa（P＞0.05） Conclusion: The new form of IVOX seems to be sucessful in improving hypoxic and hypercapnia but it is nessesary to further improve its efficiency along with bionics