肿瘤标记物CA199、CEA和CA125在胰腺癌诊断中的价值

Values of CA199、CEA and CA125 in diagnosis of pancreatic carcinoma

摘要: 目的:探讨CA199、癌脉抗原(CEA)、CA125及其联合检测对胰腺癌的诊断意义。方法:30例胰腺癌患者,男女各15例,年龄(56.4±8.2)岁;同期住院的胆囊息肉患者30例,男女各15例,年龄(52.1±7.6)岁。采用放射免疫分析法测定上述指标,并进行统计分析。结果:胰腺癌组血清CA199、CEA含量与对照组血清CA199、CEA有显著性差异(P<0.01,P<0.05),胰腺癌患者阳性率分别为83.3%,46.7%;胰腺癌组血清CA125含量与对照组血清CA125无显著性差异(P>0.05);CA199、CEA联合检测总阳性率可达96.7%。结论:CA199、CEA联合检测有利于胰腺癌的临床诊断。

Abstract: Objective:To investigate the value of combined detection of CA199、 CEA and CA125 in diagnosis of pancreatic carcinoma.Methods: The serum levels of CA199、 CEA and CA125 in 30 cases of pancreatic cancer and 30 cases control group were detected and statistically analyzed.Results: Serum CA199、 CEA level in pancreatic cancer patient were significantly higher than those in control group（P＜0.01,P＜0.05）.There were no significant difference between pancreatic cancer group and control group in the level of Serum CA125（P＞0.05）.The positive rate could increased to 96.7% by combined test of serum CA199、 CEA.Conclusion: Combined test of serum CA199 and CEA is a valuable method in diagnosis of pancreatic carcinoma.