中长链脂肪酸食用油对高甘油三酯血症患者体重和体脂的影响
Effects of medium and long chain triacylglycerol on body weight and body fat of hypertriglycerolemia patients with different body mass indexes
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摘要: 目的: 研究中长链脂肪酸与长链脂肪酸食用油对不同体重指数(bodymassindex,BMI)的高甘油三酯血症患者体重、体脂和血甘油三酯的影响。方法: 高甘油三酯血症患者101例(男性67例,女性34例),年龄(52.05±13.20)岁,BMI(26.22±3.68)kg/m2,随机分为2组,分别食用长链脂肪酸食用油(n=50)和中长链脂肪酸食用油(n=51),分别于试验前和试验第8周后进行人体测量,腹部CT扫描和血生化检查。按BMI<24kg/m2,BMI24~27.9kg/m2和BMI≥28kg/m2分为3组,观察并比较各检测指标的变化。结果: 中长链脂肪酸食用油较长链脂肪酸食用油对高甘油三酯血症患者体重降低、体脂肪减少和血甘油三酯降低作用明显(P<0.05)。中长链脂肪酸食用油对BMI24~27.9kg/m2人群的减轻体重、减少皮下脂肪和内脏脂肪的作用比BMI<24kg/m2和≥28kg/m2的人群效果明显(P<0.05)。结论: 中长链脂肪酸食用油可用于体重超重的高甘油三酯血症患者辅助控制体重和血脂。Abstract: Objective: To investigate the effects of medium and long chain triacylglycerol(MLCT)and long chain triacylglycerol(LCT)on body weight,body fat and serum triglyceride of hypertriglycerolemia patients with different body mass indexes(BMI). Methods: One hundred and one hypertriglycerolemia patients were recruited in this study.Their age was(52.05±13.2)years and their BMI was(26.22±3.68)kg/m2.The patients were randomly assigned to either MLCT group(n=51)or LCT group(n=50)according to BMI to receive MLCT or LCT for 8 weeks.Anthropometric variable measurement,umbilical CT scanning and blood chemistry were performed to observe changes in body weight,body fat and serum triglyceride before and after intervention with MLCT or LCT. Results: MLCT diet led to a significant decrease in body weight,body fat and triglyceride concentration compared with LCT diet(P<0.05). Conclusion: MLCT is a good diet for overweight hypertriglycerolemia patients to reduce their body weight,body fat and serum triglyceride.
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