冠心病患者尸检冠状动脉与脑动脉粥样硬化程度相关性分析

A corelation analysis on the degree of coronary and cerebral artery atherosclerosis in 67 autopsy patients

  • 摘要: 目的:对比观察脑动脉系统中较大动脉粥样硬化状况,以间接了解冠状动脉粥样硬化(CAS)的程度。方法:对67例连续冠心病患者47~95(75.4±9.1)岁,尸检材料中CAS和脑动脉粥样硬化程度(包括颈内动脉粥样硬化,ICA;椎基底动脉粥样硬化,VBA;大脑中动脉粥样硬化,MCA)的相关性进行分析。结果:总体分析中,CAS与ICA、VBA程度均呈显著正相关关系(P均<0.05);其中,呈显著正相关关系者有冠心病无高血压者44例的CAS与ICA、VBA及MCA;冠心病合并心梗21例的CAS与VBA及MCA(P<0.05);惟合并高血压者23例的CAS与ICA、VBA及MCA程度的相关关系不显著(P>0.05)。结论:本组ICA、VBA及MCA与CAS程度具有显著正相关系,在一定程度上可反映CAS状况,临床工作中可加以综合判断以间接了解CAS的程度。

     

    Abstract: Objective:To evaluate the relationship between the degree of cornnary artery atherosclerosis and that of the cerebral arteries.Methods:67 autopsy patients with coronary heart disease (mean age 75.4±9.1, range 47-95 years) were investigated corelatively for the degree of CAS and cerebral artery atherosclerosis (including internal carotid artery, ICA; vertebrobasilar artery, VBA; and middle cerebral artery, MCA). Results:(1)As a whole, the degree of CAS was closely related to that of ICA and VBA (P<0.05);(2)44 CHD cases without hypertension gave a significant-corelarion between CAS and ICA and VBA (P<0.05);(3)21 cases complicated with myocardial infarction also revealed a positive relation between CAS and VBA and MCA (P<0.05);(4)But in 23 patients complicated with hypertension, there was no significant corelation (P>0.05). Conclusion:The above data present an obvious positive corelation in the degree of CAS and ICA, VBA and MCA, and the severity of cerebral artery atherosclerosis may reflect the status of CAS.

     

/

返回文章
返回