Abstract: Objective To investigate the cirrhosis-related knowledge and awareness of patients’ health education in nurses from departments of gastroenterology and hepatobiliary surgery in order to provide a better basis for carrying out health education. Methods Cirrhosis-related knowledge and awareness of patients’ health education were investigated in 60 nurses from department of gastroenterology and 24 nurses from department of hepatobiliary surgery using questionnaires. Results The nurses had a moderate level in cirrhosis-related knowledge.The scores of cirrhosis-related knowledge were different in nurses with different professional titles and working hours（P＜0.05）.The majority of nurses were fully aware of health education,but they were not satisfied with the conditions for implementing health education. Conclusion Nurses in departments of gastroenterology and hepatobiliary surgery should improve their cirrhosis-related knowledge.At present,they have no sufficient time as well as health education and communication skills.Patients and their relatives do not fully understand and believe nurses.The publicity materials are insufficient in departments to carry out health education of patients.