Abstract: Objective To observe the chest CT features of pulmonary aspergillosis in patients with non-severe immunologic deficiency.Methods Chest CT findings and features of pulmonary aspergillosis diagnosed in our hospital from August 2005 to August 2010 in 25 patients with non-severe immunologic deficiency were retrospectively analyzed.Results Of the 25 patients with different CT findings,12 were found to have air cresent sign or cavity-like nodular lesions,6 had local or multiple soft tissue shadows with irregular shapes,2 had disseminated foci,and 11 had sporadic calcification.Conclusion CT findings of pulmonary aspergillosis in patients with non-severe immunologic deficiency include local or multiple nodular lesions with irregular shapes,ground glass opacities,patchy attenuations,air cresent sign or cavity.Pulmonary aspergillosis in patients with non-severe immunologic deficiency should be discriminated with inflammation,tumors,and tuberculosis.Its final diagnosis depends on lung biopsy.