Abstract: Objective:Although PTCA has been used to treat patient with AMI of various stages, it remains controversial in reducing mortality and improving LV unction.Methods: One hundred patients with AMI and studied by coronary angiography during the admission were divided into 3 groups, rescue PTCA（13 cases）, elective PTCA（29 casee） and conservative treatment（57 cases）. There was only one direct PTCA. Mortality, reinfarction, angina, LV function and PTCA success rate were compaired among the 3 groups. Results: Of the 13 cases of rescue PTCA, 8 were successful. The chest pain was relieved, ST segment returned to baseline and hypotension was corrected after recanalization. In comparison with elective PTCA, however, the rescue PTCA had low success rate, severe residual stenosis, low LVEF and high mortality, post infarct angina and reinfarction rates. Elective PTCA also compared favourably with conservative treatment, which had higher LVEF and lower mortality and reinfarction rates. We did only 1 immediate PTCA, but it achieved a good result.Conclusion: rescue PTCA can be used to recanalize patients with failed thrombolysis. The short term effect is good if it is successful. However, its long term effect is not as good as elective PTCA. Elective PTCA is not only safer than rescue PTCA, but is is also better than conservative treatments.