Abstract: Objective To report the effect of chemically extracted acellular nerve allograft（CEANA） on lacerated brachial plexus nerve defects in 5 cases.Methods Five patients with lacerated brachial plexus nerve defects were treated with CEANA from Feb.25,2004 to Mar.5,2009 in our hospital.Eight nerve allografts were used with an average length of 3.1cm（ranging 2-4cm） to repair defects of C5,C6,upper trunk,middle trunk and posterior division of the upper trunk in 2,3,1,1 and 1 patients,respectively.The patients were followed up for sensation and motion with brachial plexus ultrasonography,MRI and EMG,respectively.Results The mean follow-up time was 40.4months（ranging 14-74months）.Excellent and good outcome was achieved in 3 and 1 patients,respectively,with no improvement observed in 1 patient.Of the 8 nerve allografts used,4 functioned excellently and 2 functioned well.Conclusion CEANA can be used in repair of lacerated brachial plexus nerve defects with a rather good therapeutic effect,thus laying a foundation for its further application in clinical practice.